T
tietoisuutta fibroon
Vieras
Onko teiltä koskaan mittailtu kudosrauta-arvoja? Tuskinpa juuri, koska lääkärit eivät tajua siitä yhtään mitään. Mm. sitä, en sen vähäisyys haittaa dopamiini - ja serotoniinituotantoa aivoissa.
Lueskelin jotain fibroketjua, jossa Jonsered kertoo myös omaavansa ADHD:n fibron lisäksi. MOLEMMISSA tiedetään tutkimusten perusteella, että aivoissa on rauta-aineenvaihdunnan häiriöitä. Kumma että fibrot ovat usein naisia, jotka muutenkin ovat taipuvaisia rautavajeeseen kehossa??
Kannattaa pistää tohtorit koville ja vaatia laajat rautatilannetta koskevat testit (täysi anemiapaneeli, mutta etenkin ferritiini). Hb ei tässä tapauksessa kerro yhtään mitään, sillä se laskee vasta loppuvaiheessa kun kehossa ei ole yhtään rautaa revittäväksi.
___Tässä tutkimus, jossa todetaan alhaisen kudosraudan (ferritiini), arvo alle 50 ng/ml nostavan fibromyalgian riskiä 6,5 -kertaiseksi. Oma arvoni on 14, kun viitearvot ovat 13-150!!
Association between serum ferritin [stored iron] level and fibromyalgia syndrome Source: European Journal of Clinical Nutrition, Jan 20, 2010
by O Ortancil, et al.
January 24, 2010
[Note: Ferritin is an iron-storage protein in cells. It binds to iron, keeps it in a dissolvable state, and makes it non-toxic to the cells around it.]
Background/Objectives:
Iron is essential for a number of enzymes involved in neurotransmitter synthesis.
Analysis of cerebrospinal fluid in fibromyalgia syndrome (FMS) has shown a reduction in the concentration of biogenic amine metabolites, including dopamine, norepinephrine and serotonin.
This study aimed to investigate the association of ferritin with FMS.
Subjects/Methods: A total of 46 patients with primary FMS participated in this case-control study, and 46 healthy females who were age matched to the patients were used as the control group. Venous blood samples collected from all subjects were used to evaluate serum ferritin, vitamin B12 and folic acid levels.
Results: The mean serum ferritin levels in the fibromyalgia (FM) and control groups were 27.3+/-20.9 and 43.8+/-30.8 ng/ml, respectively, and the difference was statistically significant (P=0.003). Binary multiple logistic regression analysis with age, body mass index, smoking status and vitamin B12, as well as folic acid and ferritin levels showed that having a serum ferritin level of less than 50 ng/ml caused a 6.5-fold increased risk for FMS.
Conclusions: Our study implicates a possible association between FM and decreased ferritin level, even for ferritin in normal ranges.
We suggest that iron as a cofactor in serotonin and dopamine production may have a role in the etiology of FMS.
Lueskelin jotain fibroketjua, jossa Jonsered kertoo myös omaavansa ADHD:n fibron lisäksi. MOLEMMISSA tiedetään tutkimusten perusteella, että aivoissa on rauta-aineenvaihdunnan häiriöitä. Kumma että fibrot ovat usein naisia, jotka muutenkin ovat taipuvaisia rautavajeeseen kehossa??
Kannattaa pistää tohtorit koville ja vaatia laajat rautatilannetta koskevat testit (täysi anemiapaneeli, mutta etenkin ferritiini). Hb ei tässä tapauksessa kerro yhtään mitään, sillä se laskee vasta loppuvaiheessa kun kehossa ei ole yhtään rautaa revittäväksi.
___Tässä tutkimus, jossa todetaan alhaisen kudosraudan (ferritiini), arvo alle 50 ng/ml nostavan fibromyalgian riskiä 6,5 -kertaiseksi. Oma arvoni on 14, kun viitearvot ovat 13-150!!
Association between serum ferritin [stored iron] level and fibromyalgia syndrome Source: European Journal of Clinical Nutrition, Jan 20, 2010
by O Ortancil, et al.
January 24, 2010
[Note: Ferritin is an iron-storage protein in cells. It binds to iron, keeps it in a dissolvable state, and makes it non-toxic to the cells around it.]
Background/Objectives:
Iron is essential for a number of enzymes involved in neurotransmitter synthesis.
Analysis of cerebrospinal fluid in fibromyalgia syndrome (FMS) has shown a reduction in the concentration of biogenic amine metabolites, including dopamine, norepinephrine and serotonin.
This study aimed to investigate the association of ferritin with FMS.
Subjects/Methods: A total of 46 patients with primary FMS participated in this case-control study, and 46 healthy females who were age matched to the patients were used as the control group. Venous blood samples collected from all subjects were used to evaluate serum ferritin, vitamin B12 and folic acid levels.
Results: The mean serum ferritin levels in the fibromyalgia (FM) and control groups were 27.3+/-20.9 and 43.8+/-30.8 ng/ml, respectively, and the difference was statistically significant (P=0.003). Binary multiple logistic regression analysis with age, body mass index, smoking status and vitamin B12, as well as folic acid and ferritin levels showed that having a serum ferritin level of less than 50 ng/ml caused a 6.5-fold increased risk for FMS.
Conclusions: Our study implicates a possible association between FM and decreased ferritin level, even for ferritin in normal ranges.
We suggest that iron as a cofactor in serotonin and dopamine production may have a role in the etiology of FMS.
Asia ei olekaan niin yksioikoinen, että kaikilla fibroilla olisi raudanpuutetta ja toisinpäin. Mutta yhteys on huomattu, ja ehkä se on genetiikka joka sitten pistää aivot solmuun tietyissä olosuhteissa.
